Tag: 爱上海龙凤爱后花园松江

  • Top 10 Pharma Deals in Last Five Years

    first_imgAnnounced DateValue in $ millionAcquirerAcquired Firm NameCountryNameTarget nation 21 November 201111,017.1Gilead Sciences IncUnited StatesPharmasset IncUnited States 20 June 201456,064.4AbbVie IncUnited StatesShire plcUnited Kingdom 22 April 201454,652.Valeant Pharmaceuticals International IncCanadaAllergan IncUnited States 22 April 201423,050Novartis AG, GlaxoSmithKline plcSwitzerland, United KingdomGlaxoSmithKline’s oncology portfolio, R&D activities & AKT inhibitor rights / Novartis’ vaccines businessUnited Kingdom 6 May 201414,200Bayer AGGermanyMerck & Co Inc (Consumer Care Business)United States 21 July 201135,017.9Express Scripts IncUnited StatesMedco Health Solutions IncUnited Statescenter_img 30 June 201310,248.2Amgen IncUnited StatesONYX Pharmaceuticals IncUnited States On Monday, 14 July, Pharmaceutical Company Mylan Inc announced the acquisition of Abbott Laboratories in markets outside the United States, with an aim to cut their tax bill using tax inversion methods.In the past too many such deals have been seen and big names have merged with or acquired smaller or sick companies for either tax evasions or expansions.Here’s the list of top 10 pharmaceutical merger and acquisition deals announced in the last five years. However, the list excludes spin off’s.Announced DateAnnounced DateValue in $ millionValue in $ millionAcquirerAcquirerAcquired FirmAcquired FirmAnnounced DateNameValue in $ millionCountryAcquirerNameAcquired FirmTarget nationAnnounced Date18 Feb 2014Value in $ million28,407AcquirerActavis plcAcquired FirmUnited StatesForest Laboratories IncUnited StatesAnnounced Date22 April 2014Value in $ million54,652.AcquirerValeant Pharmaceuticals International IncAcquired FirmCanadaAllergan IncUnited StatesAnnounced Date22 April 2014Value in $ million23,050AcquirerNovartis AG, GlaxoSmithKline plcAcquired FirmSwitzerland, United KingdomGlaxoSmithKline’s oncology portfolio, R&D activities & AKT inhibitor rights / Novartis’ vaccines businessUnited KingdomAnnounced Date6 May 2014Value in $ million14,200AcquirerBayer AGAcquired FirmGermanyMerck & Co Inc (Consumer Care Business)United StatesAnnounced Date20 June 2014Value in $ million56,064.4AcquirerAbbVie IncAcquired FirmUnited StatesShire plcUnited KingdomAnnounced Date30 June 2013Value in $ million10,248.2AcquirerAmgen IncAcquired FirmUnited StatesONYX Pharmaceuticals IncUnited StatesAnnounced Date19 May 2011Value in $ million13,682AcquirerTakeda Pharmaceutical Co LtdAcquired FirmJapanNycomed SCA SICARSwitzerlandAnnounced Date21 July 2011Value in $ million35,017.9AcquirerExpress Scripts IncAcquired FirmUnited StatesMedco Health Solutions IncUnited StatesAnnounced Date21 November 2011Value in $ million11,017.1AcquirerGilead Sciences IncAcquired FirmUnited StatesPharmasset IncUnited StatesAnnounced Date29 August 2010Value in $ million24,476.7AcquirerSanofi-Aventis SAAcquired FirmFranceGenzyme CorpUnited States Source: Dealogic 19 May 201113,682Takeda Pharmaceutical Co LtdJapanNycomed SCA SICARSwitzerland 29 August 201024,476.7Sanofi-Aventis SAFranceGenzyme CorpUnited States 18 Feb 201428,407Actavis plcUnited StatesForest Laboratories IncUnited Stateslast_img read more

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  • Why is Vijayashanthi more talkedabout than Rashmika Mandanna in Sarileru Neekevvaru

    first_imgVijayashanthi and Rashmika MandannaCollage of photos taken from Twitter and FacebookVijayashanthi (Vijayashanti) has put all the rumours about her role in Sarileru Neekevvaru to rest. But many wonder why her role is more talked-about than Rashmika Mandanna, who appears as Mahesh Babu’s love interest.Vijayashanthi was one of the most popular actresses in the 1980s and 90s and is known for doing female-centric movies. The yesteryear actress is currently focused on politics and often makes it to the headlines for her aggressive political remarks against her opponents. She is set to make a comeback to acting with Sarileru Neekevvaru. She is now doing heavy workouts to get herself fit for the role in it.It was rumoured that Sarileru Neekevvaru has a role that perfectly suits Vijayashanthi and director Anil Ravipudi desperately wanted her to play this pivotal character. The actress quoted Rs 5 crore to be a part of this project and this is the highest amount ever paid to any actress down south. The makers of the film have reportedly agreed to pay this huge amount to bring her on board.Vijayashanthi is said to be playing a powerful faction leader and she will take on Jagapathi Babu in Sarileru Neekevvaru. She is also said to be performing action sequences in the movie. One report has claimed she will appear as Mahesh Babu’s mother. Another buzz was that she is playing the role of Rashmika Mandanna’s mother and Prince appears as her security guard.But in an interview to a Telugu daily, Vijayashanthi has put an end to all the speculations about her role in Sarileru Neekevvaru. She said that she is neither essaying a negative role nor playing Mahesh Babu’s mother in the movie. She revealed that she is playing a supporting role with substance and her character has no relation to his role in this film.Usually, the roles of heroes and heroines create a lot of buzz in the media. The supporting roles rarely get highlighted, unless it is kind of role played by Ramya Krishnan in Baahubali film series. However, Ever since Vijayashanthi is on board, a lot has been written and spoken about the details of her role and remuneration. The buzz about her character is much bigger than that Rashmika Mandanna’s role.Only the makers of Sarileru Neekevvaru can reveal the hype behind Vijayashanthi’s role. Or we have to wait for the release of the movie, which is scheduled to hit the screens during Sankranti 2020.last_img read more

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  • Pen draws flexible circuits using halfmeter long carbon nanotube fibers

    first_imgResearchers use a pen to draw half-meter-long carbon-nanotube-based fibers. The technique could be used to fabricate flexible electronic circuits. Credit: Huang, et al. ©2015 American Chemical Society © 2015 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Researchers report progress in development of carbon nanotube-based continuous fibers Diagram of the writing process and images of the ink, pen, and fibers. Credit: Huang, et al. ©2015 American Chemical Society Patterns drawn by hand showing the precision with which the fibers can be controlled. Credit: Huang, et al. ©2015 American Chemical Society In the future, the researchers hope to expand the drawing technique to use different types of ink for different purposes.”We are now working on enabling more functions in the fiber,” Wu said. “For example, one possibility is semiconducting fibers drawn from a pen tip for flexible device applications.” (Phys.org)—While it may look like researchers from Tsinghua University in Beijing are sketching out an idea for a circuit on a piece of paper, they’re actually using a special pen that draws real circuits using carbon-nanotube-based ink.center_img When writing, the pen is lifted off the paper to stretch and suspend the fibers, which can then be laid down on the substrate in the desired position. The researchers demonstrated that complex fiber patterns can be drawn by hand, and they predict that even greater precision can be achieved using advanced mechanical devices.The researchers also showed that increasing the polymer concentration of the ink increases the diameter of the nanotube fibers from 300 nm to 3 µm. In general, thinner fibers have better conductivity than thicker ones due to their better fiber orientation. Tests show that the highly conductive carbon nanotube fibers also exhibit excellent mechanical flexibility. At first, the researchers expected that the ultralong carbon nanotube fibers should maintain their conductivity after bending and distortion. Somewhat surprisingly, their tests showed that the fibers actually exhibit an increase in conductivity after bending—about a 30% increase after 1000 bending cycles. The researchers propose that the stress caused by bending deforms the polymers and improves nanotube alignment, which in turn increases conductivity. Journal information: Nano Letters More information: Sihan Huang, et al. “Direct Writing of Half-Meter Long CNT Based Fiber for Flexible Electronics.” Nano Letters. DOI: 10.1021/nl504150a Citation: Pen draws flexible circuits using half-meter long carbon nanotube fibers (2015, February 20) retrieved 18 August 2019 from https://phys.org/news/2015-02-pen-flexible-circuits-half-meter-carbon.html This technique, called “fiber drawing,” has previously been used to construct patterns, but the fiber length is usually very short at just a few millimeters, and the drawing speed is typically very slow. These drawbacks limit its use in circuit fabrication.In the new study, the researchers demonstrated that their new pen can draw carbon nanotube fibers that are more than a half of a meter long with fast drawing speeds of up to 10 cm/second. Their work is published in a recent issue of Nano Letters.Due to the nanotube fibers’ high conductivity and excellent mechanical flexibility, the researchers predict that the fibers could serve as the fundamental building blocks for a wide variety of flexible electronic devices, such as wearable electronics, flexible touch displays, flexible solar cells, RFIDs, and 3D devices.While the pen itself is an ordinary commercial pen, the ink consists of a combination of electrically conductive carbon nanotube fibers and a viscous polymer solution called polyethylene oxide (PEO). The viscous PEO is highly elastic and mechanically strong, which allows it to pull long nanotube fibers from the solution during the writing process. “The drawing technique allow us to achieve very long carbon nanotube fibers mainly due to the high molecular weight of the polymer and high viscosity of the precursor solution as ink,” coauthor Hui Wu, Associate Professor at Tsinghua University, told Phys.org. Explore furtherlast_img read more

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  • Indian womens team has a strong attack Chief coach Mathias Ahrens

    first_imgIndian women’s hockey team chief coach Mathias Ahrens said that his forwards are preparing well and have a strong attack to take on other teams in the Hockey World League (HWL) Semi-Final, to be played here from June 20 to July 5.“The teams will be evenly placed and all will depend on the initial pressure. On that front we have a strong attack and I am confident of a good start,” said Ahrens on Monday. “The girls realise that continuing ball possession in the opponents D is important and the team is working on short passes and their reaction time once in the D as time will be the key. They have to enter, finish the job in a matter of seconds.”India have been grouped in Pool B with hosts Belgium, Australia, New Zealand and Poland. They will open their campaign against Belgium on June 20. “Our first match is against the Belgium. They will have just one advantage over us, which will be playing in front of their home crowd,” said German.last_img read more

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  • Are Electric Scooters Awesome or Terrible A Look at the Pros and

    first_img Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Opinions expressed by Entrepreneur contributors are their own. 6 min read August 20, 2018 First it was the people of San Francisco who vandalized electric kick scooters in all kinds of unimaginable ways. Now, LA residents are showing their frustration by setting scooters on fire and throwing them into the ocean, trash cans and even toilets.Related: Check Out This Futuristic, and Dangerous Looking, Police HoverbikeAt the same time, e-scooter operators like Bird, Lime, Spin and Skip keep rolling out new fleets almost every day and cities are trying to find a compromise that satisfies both sides.E-scooter fleets solve the problem of the last mile commute without breaking a sweat and not worrying whether your vehicle will be stolen. However, the emergence of e-scooter sharing fleets has created many problems for cities and people are frustrated about the way e-scooters are being used. It is time to evaluate the pros and cons of e-scooter fleets and see where the industry is heading.Pros of e-scooter fleetsFor the end user, the benefits are self evident. It is a perfect way to easily commute short distances. All you need to rent an e-scooter is an app, and you can leave one almost anywhere, as long as you follow the guidelines for using and parking e-scooters. Unfortunately, we are already seeing that e-scooters are often left in random places, blocking pedestrian pathways. Using an e-scooter is also quite cheap — it costs around $1 per trip plus 15 cents per minute. In addition, scooters are fun to ride and are better for the environment than other modes of transportation that run on fossil fuels.For the potential fleet operators, the main benefit is the booming billion-dollar industry and its various opportunities to scale quickly. According to Anand Sanwal, the CEO of tech data and analytics firm CB Insights, “There are underlying trends such as a decline in car ownership and the shift to living in urban areas which also suggest that the urban transport market that Bird and others are attacking is growing.”Related: Are Autonomous Vehicle Tests a Public Hazard?Secondly, according to one of the investors in Bird, Mark Suster, as an e-scooter operator you get tons of valuable data by tracking where the vehicles are and where people tend to pick and leave their e-scooters. This in turn can help cities to build their cities better.Thirdly, as a fleet owner you will be able to create new opportunities to earn money. Bird, Lime and others are giving people the opportunity to increase their income by collecting and charging e-scooters during the night. In addition to earning money, these people will be part of the innovation movement that pushes the industry to build better e-scooters with longer battery life, as this is the main obstacle at the moment.Finally, e-scooters are not just toys for tech bros and hipsters. According to a new study made about the new micro-mobility services, including e-scooters, a majority (70 percent) of people across the U.S. view electric scooters positively. And women are expected to support and adopt e-scooters more than bike sharing, which is more used by men. The study doesn’t say why that is, but this Wired article suggests that e-scooters are easier to ride in heels and skirts. Also, e-scooters appear to be easier to operate, feel safer and don’t require any physical exertion. This founding again confirms the huge potential of the e-scooter sharing market.Related: Uber Invests in Scooter Startup LimeCons of e-scooter fleetsAs stated earlier, e-scooter fleets are far from perfect and the main danger is growing too fast. Since there is a race out there for who can take over a market first, there is a high probability that companies are cutting corners. This may result in unreliable hardware and software solutions. In order to launch a reliable fleet, you need every component of the e-scooter fleet chain to be working.Another danger of moving too fast is the pushback from cities. So far, cities have not banned e-scooters completely, but some are very worried and the approval process may take years rather than months. Frustrations in San Francisco led the city attorney to say, “San Francisco has had enough of the mantra — move fast and break things.”Cities are worried about public areas getting filled with broken e-scooters, as has happened with e-bikes in China. We are already seeing big players like Ofo and Mobike pulling out of dockless bike sharing in Washington, D.C. due to city regulations. Will the same thing happen to e-scooters?Related: Are Self-Driving Cars Finally Ready for Consumers? What Entrepreneurs Need to Know.At the moment, there is an issue with reliability of e-scooters with short battery life and their destruction by bad terrain and street conditions. In fact, e-scooter fleets need good weather conditions and are very susceptible to bad terrain.Finally, are e-scooters really eco-friendly? Although the e-scooters are better for the environment, the lithium battery lifetime on e-scooters is quite short and need to be replaced every 300 to 1000 charges depending on the battery provider. According to SF Weekly, fleet operators claim to have battery recycling programs in place, but in San Francisco there currently is no processing center that deals with these kind of batteries.Besides the processing problems of lithium batteries, there is the issue of picking them up and charging them. People who make extra money by charging the e-scooters still need to use cars and vans, so in a way it is a zero sum game.Currently there is a lot fuss around e-scooter sharing and it will continue for a while, since cities need to figure out how to accommodate the rising number of e-scooters in a safe and non-disruptive way. In turn, electric kick scooter operators need to improve their technological solutions and the way they roll out their services. All in all, the e-scooter scene is changing by the minute and it will be interesting to see who will be first on the market and how will people respond. Growing a business sometimes requires thinking outside the box. Register Now »last_img read more

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  • Watch out for these roadworks across Newcastle Borough this week

    first_imgGet the biggest Daily stories by emailSubscribeSee our privacy noticeThank you for subscribingSee our privacy noticeCould not subscribe, try again laterInvalid Email Drivers are being warned to expect traffic and travel delays due to roadworks across Newcastle Borough this coming week. Motorists hitting the roads of the area on Monday morning can expect a raft of delays and road closures waiting for them. The following roadworks are taking place in Newcastle Borough between Monday September 17 and Sunday September 23. This list contains only the roadworks considered to be most likely to cause delays on key routes as well as those involving road closures and temporary traffic lights. It is not exhaustive and does not feature some minor or emergency repairs that come up after publication. Other roadworks may finish or start before schedule or be cancelled altogether. If you only want information about roadworks in a different area of North Staffordshire and South Cheshire, visit the links below, otherwise scroll down for the roadworks most likely to disrupt your journey in Newcastle Borough in the coming week All information from Highways England, local authorities and utility companies. Read MoreRoadworks in North Staffordshire and South Cheshire (Sep 17-Sep 23 2018) Staffordshire Moorlands M6, A500 and A50 South Cheshire M6 to shut for up to 24 hours Stafford Borough and Uttoxetercenter_img Stoke-on-Trent Full list of roadworks Newcastle Borough Newcastle Borough: B – M Baldwins Gate: Multi-way traffic lights on A53 Newcastle Road near junction with A51 from September 14 until September 18. Balterley: Road closures and roadworks on B5500 Waggon Road between Peel Avenue and Deans Lane (over the M6) – 24 hour closures from September 7 until September 10 and September 14 and September 17 Bradwell: Multi-way traffic lights on Bradwell Lane at junction with Clare Avenue from September 19 until September 21 Bradwell: Two way traffic lights along Bradwell Lane until November 30 Cross Heath: Roadworks and road closures on A34 Liverpool Road near junction of Lower Milehouse Lane until October 12. Kidsgrove: Give and take traffic control on The Avenue in Clough Hall from September 20 until September 24 Madeley: Two way traffic lights on New Road from September 19 until September 29 Madeley Park: Two way traffic signals on Manor Road near entrance to Farcroft from September 14 until September 18. May Bank: Two way traffic signals on Basford Park Road near May Bank Infants School from September 7 until September 13. Mow Cop: Roadworks/road closure on Mow Cop Road, Mow Cop from the junction of Mow Cop Road from September 17 until October 26 Near M6: Multi-way traffic signals at junction of B5500 Nantwich Road at junction with Limbrick Road until October 12 Read MoreOpening date revealed for this AMAZING new cafe bar offering craft ales and light bites N Newcastle: Multi-way signals on Keele Road near Orme Road from September 13 until September 17. Newcastle: Roadworks and lane closure on Barracks Road from September 14 until September 18. Newcastle: Roadworks and lane closure on Barracks Road on September 20 Newcastle: Roadworks and lane closure on Brunswick Street from September 14 until September 18. Newcastle: Roadworks and lane closure on Brunswick Street on September 21 Newcastle: Multi-way traffic lights on Etruria Road near the junction with The Avenue from September 16 until September 23 Newcastle: Roadworks and lane closure on London Road outside Holy Trinity Community Centre from September 17 until September 19. Newcastle: Roadworks and road closure on Milborne Drive until October 5. Newcastle: Two way traffic lights on Tansey Way from September 19 until September 25 Newcastle: Roadworks and road closure on Whitfield Avenue until October 9. Read MoreMother and two babies rescued after car leaves A50 P-S Porthill: Two way traffic lights on High Street from September 20 until September 24 Porthill: Multi-way traffic signals on Oakland Avenue and Inglewood Drive from September 17 until October 12 Silverdale: Multi-way traffic lights on High Street from junction with Mill Street to Parkfields Close from September 7 until October 18 Silverdale: Roadworks and Road closure on Hollywood Lane until March 20 2019 Silverdale: Multi-way traffic signals on Mill Street from the junction with Newcastle Street to the junction with High Street from August 29 until September 25. Silverdale: Roadworks and road closure on Park Road from September 11 until September 17 Want to keep up to date with the latest traffic and travel news?Each day Stoke-on-Trent Live journalists bring you the latest news on the roads and railways across Stoke-on-Trent, North Staffordshire, South Cheshire and further afield to help keep you on the move. For the very latest updates on roads including the M6, A500, A50 and more, visit our dedicated traffic and travel news channel here. We also run a live news feed each weekday, which you can access on our website’s homepage from 7am to 9pm from Monday to Friday. And for more as-we-get-it updates on the roads across the region and beyond, join The Sentinel’s traffic and travel Facebook group here.last_img read more

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